腹主动脉瘤（AAA）是一种血管疾病，其中主动脉的一部分肿大，削弱其壁并可能破裂血管。腹部超声已用于诊断，但由于其图像质量和操作员的依赖性有限，通常需要进行CT扫描进行监测和治疗计划。最近，腹部CT数据集已成功用于训练深神经网络以进行自动主动脉分割。因此，可以利用从这项解决的任务中收集的知识来改善我们的AAA诊断和监测分段。为此，我们提出了Cactuss：一种常见的解剖CT-US空间，它是CT和美国模式之间的虚拟桥梁，以实现自动AAA筛选超声检查。仙人掌利用公开可用的标记数据来学习基于从美国和CT继承属性的中介表示。我们在此新表示中训练分割网络，并采用附加的图像到图像翻译网络，使我们的模型能够在真实的B模式图像上执行。与完全监督的方法进行的定量比较证明了在骰子评分和诊断指标方面的能力，这表明我们的方法还满足了AAA扫描和诊断的临床要求。

我们提出了一种新的方法来自动校准跟踪的超声探针。为此，我们设计了一个自定义幻影，该幻影由9个具有不同高度的圆锥体组成。这些技巧用作在多个扫描之间匹配的关键点。我们使用卷积神经网络提取它们，以分割每个超声框架中的锥体，然后在整个扫描中跟踪它们。使用基于图像的技术，使用RANSAC和后来完善的精制来估计校准。我们的幻影可以是3D打印的，并且比最先进的方法具有许多优势。幻影设计和算法代码可在线免费获得。由于我们的幻影本身不需要跟踪目标，因此与当前使用的技术相比，易用性的提高。如我们的实验所示，全自动方法概括为新的探针和不同的供应商。我们的方法产生的结果与域专家获得的校准相当。

From smoothly pursuing moving objects to rapidly shifting gazes during visual search, humans employ a wide variety of eye movement strategies in different contexts. While eye movements provide a rich window into mental processes, building generative models of eye movements is notoriously difficult, and to date the computational objectives guiding eye movements remain largely a mystery. In this work, we tackled these problems in the context of a canonical spatial planning task, maze-solving. We collected eye movement data from human subjects and built deep generative models of eye movements using a novel differentiable architecture for gaze fixations and gaze shifts. We found that human eye movements are best predicted by a model that is optimized not to perform the task as efficiently as possible but instead to run an internal simulation of an object traversing the maze. This not only provides a generative model of eye movements in this task but also suggests a computational theory for how humans solve the task, namely that humans use mental simulation.

The outburst of COVID-19 in late 2019 was the start of a health crisis that shook the world and took millions of lives in the ensuing years. Many governments and health officials failed to arrest the rapid circulation of infection in their communities. The long incubation period and the large proportion of asymptomatic cases made COVID-19 particularly elusive to track. However, wastewater monitoring soon became a promising data source in addition to conventional indicators such as confirmed daily cases, hospitalizations, and deaths. Despite the consensus on the effectiveness of wastewater viral load data, there is a lack of methodological approaches that leverage viral load to improve COVID-19 forecasting. This paper proposes using deep learning to automatically discover the relationship between daily confirmed cases and viral load data. We trained one Deep Temporal Convolutional Networks (DeepTCN) and one Temporal Fusion Transformer (TFT) model to build a global forecasting model. We supplement the daily confirmed cases with viral loads and other socio-economic factors as covariates to the models. Our results suggest that TFT outperforms DeepTCN and learns a better association between viral load and daily cases. We demonstrated that equipping the models with the viral load improves their forecasting performance significantly. Moreover, viral load is shown to be the second most predictive input, following the containment and health index. Our results reveal the feasibility of training a location-agnostic deep-learning model to capture the dynamics of infection diffusion when wastewater viral load data is provided.

Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) assesses genome-wide chromatin accessibility in thousands of cells to reveal regulatory landscapes in high resolutions. However, the analysis presents challenges due to the high dimensionality and sparsity of the data. Several methods have been developed, including transformation techniques of term-frequency inverse-document frequency (TF-IDF), dimension reduction methods such as singular value decomposition (SVD), factor analysis, and autoencoders. Yet, a comprehensive study on the mentioned methods has not been fully performed. It is not clear what is the best practice when analyzing scATAC-seq data. We compared several scenarios for transformation and dimension reduction as well as the SVD-based feature analysis to investigate potential enhancements in scATAC-seq information retrieval. Additionally, we investigate if autoencoders benefit from the TF-IDF transformation. Our results reveal that the TF-IDF transformation generally leads to improved clustering and biologically relevant feature extraction.

Cross-domain graph anomaly detection (CD-GAD) describes the problem of detecting anomalous nodes in an unlabelled target graph using auxiliary, related source graphs with labelled anomalous and normal nodes. Although it presents a promising approach to address the notoriously high false positive issue in anomaly detection, little work has been done in this line of research. There are numerous domain adaptation methods in the literature, but it is difficult to adapt them for GAD due to the unknown distributions of the anomalies and the complex node relations embedded in graph data. To this end, we introduce a novel domain adaptation approach, namely Anomaly-aware Contrastive alignmenT (ACT), for GAD. ACT is designed to jointly optimise: (i) unsupervised contrastive learning of normal representations of nodes in the target graph, and (ii) anomaly-aware one-class alignment that aligns these contrastive node representations and the representations of labelled normal nodes in the source graph, while enforcing significant deviation of the representations of the normal nodes from the labelled anomalous nodes in the source graph. In doing so, ACT effectively transfers anomaly-informed knowledge from the source graph to learn the complex node relations of the normal class for GAD on the target graph without any specification of the anomaly distributions. Extensive experiments on eight CD-GAD settings demonstrate that our approach ACT achieves substantially improved detection performance over 10 state-of-the-art GAD methods. Code is available at https://github.com/QZ-WANG/ACT.

This work concerns developing communication- and computation-efficient methods for large-scale multiple testing over networks, which is of interest to many practical applications. We take an asymptotic approach and propose two methods, proportion-matching and greedy aggregation, tailored to distributed settings. The proportion-matching method achieves the global BH performance yet only requires a one-shot communication of the (estimated) proportion of true null hypotheses as well as the number of p-values at each node. By focusing on the asymptotic optimal power, we go beyond the BH procedure by providing an explicit characterization of the asymptotic optimal solution. This leads to the greedy aggregation method that effectively approximate the optimal rejection regions at each node, while computation-efficiency comes from the greedy-type approach naturally. Extensive numerical results over a variety of challenging settings are provided to support our theoretical findings.

Time series anomaly detection has applications in a wide range of research fields and applications, including manufacturing and healthcare. The presence of anomalies can indicate novel or unexpected events, such as production faults, system defects, or heart fluttering, and is therefore of particular interest. The large size and complex patterns of time series have led researchers to develop specialised deep learning models for detecting anomalous patterns. This survey focuses on providing structured and comprehensive state-of-the-art time series anomaly detection models through the use of deep learning. It providing a taxonomy based on the factors that divide anomaly detection models into different categories. Aside from describing the basic anomaly detection technique for each category, the advantages and limitations are also discussed. Furthermore, this study includes examples of deep anomaly detection in time series across various application domains in recent years. It finally summarises open issues in research and challenges faced while adopting deep anomaly detection models.

当网络条件恶化时，视频会议系统的用户体验差，因为当前的视频编解码器根本无法在极低的比特率下运行。最近，已经提出了几种神经替代方案，可以使用每个框架的稀疏表示，例如面部地标信息，以非常低的比特率重建说话的头视频。但是，这些方法在通话过程中具有重大运动或遮挡的情况下会产生不良的重建，并且不会扩展到更高的分辨率。我们设计了Gemino，这是一种基于新型高频条件超分辨率管道的新型神经压缩系统，用于视频会议。 Gemino根据从单个高分辨率参考图像中提取的信息来增强高频细节（例如，皮肤纹理，头发等），为每个目标框架的一个非常低分辨率的版本（例如，皮肤纹理，头发等）。我们使用多尺度体系结构，该体系结构在不同的分辨率下运行模型的不同组件，从而使其扩展到可与720p相当的分辨率，并且我们个性化模型以学习每个人的特定细节，在低比特率上实现了更好的保真度。我们在AIORTC上实施了Gemino，这是WEBRTC的开源Python实现，并表明它在A100 GPU上实时在1024x1024视频上运行，比比特率的比特率低于传统的视频Codecs，以相同的感知质量。

kronecker回归是一个高度结构的最小二乘问题$ \ min _ {\ mathbf {x}}} \ lvert \ mathbf {k} \ mathbf {x} - \ mathbf {b} \ rvert_ \ rvert_ {2}^2 $矩阵$ \ mathbf {k} = \ mathbf {a}^{（1）} \ otimes \ cdots \ cdots \ otimes \ mathbf {a}^{（n）} $是因子矩阵的Kronecker产品。这种回归问题是在广泛使用的最小二乘（ALS）算法的每个步骤中都出现的，用于计算张量的塔克分解。我们介绍了第一个用于求解Kronecker回归的子次数算法，以避免在运行时间中避免指数项$ o（\ varepsilon^{ - n}）$的$（1+ \ varepsilon）$。我们的技术结合了利用分数抽样和迭代方法。通过扩展我们对一个块是Kronecker产品的块设计矩阵的方法，我们还实现了（1）Kronecker Ridge回归的亚次级时间算法，并且（2）更新ALS中Tucker分解的因子矩阵，这不是一个不是一个纯Kronecker回归问题，从而改善了Tucker ALS的所有步骤的运行时间。我们证明了该Kronecker回归算法在合成数据和现实世界图像张量上的速度和准确性。